Raptor FluoroPhenyl, 5 µm, 250 x 4.6 mm HPLC Column

Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times with existing HPLC and UHPLC instrumentation.

Restek has now extended the speed and reliability of Raptor column technology into the HILIC realm with the addition of Raptor FluoroPhenyl columns. Restek’s Raptor FluoroPhenyl phase offers chromatographers the ability to run in reversed-phase or HILIC mode for a variety of compounds. The Restek Raptor FluoroPhenyl column is also amenable to LC-MS because it is extremely reliable and efficient with acidic mobile phases.

Stationary Phase Category: Pentafluorophenyl propyl (L43)
Ligand Type: Fluorophenyl
Particle: 1.8 µm, 2.7 µm, or 5 µm superficially porous particle (SPP or “core-shell” particle) silica
Pore Size: 90 Å
Carbon Load: 4% (1.8 µm), 4% (2.7 µm), 3% (5 µm)
End-Cap: no
Surface Area: 125 m²/g (1.8 µm), 130 m²/g (2.7 µm), or 100 m²/g (5 µm)

Recommended Usage:
pH Range: 2.0–8.0
Maximum Temperature: 80 °C
Maximum Pressure: 1034 bar/15,000 psi* (1.8 ?m), 600 bar/8700 psi (2.7 ?m); 400 bar/5800 psi (5 ?m)

* For maximum lifetime, recommended maximum pressure for 1.8 ?m particles is 830 bar/12,000 psi.

Properties:

• Capable of both reversed-phase and HILIC separations.
• Ideal for increasing sensitivity and selectivity in LC-MS analyses.
• Offers increased retention for charged bases.

Switch to a Raptor FluoroPhenyl LC column when:

• Limited retention and selectivity are observed on a C18 for basic compounds.
• You need increased retention of hydrophilic compounds.

Features & Benefits

• Retains hydrophobic, polar, and aromatic compounds.
• Has orthogonal selectivity to a C18.
• Exceptionally reproducible—predictable performance from every column.
• Part of Restek’s Raptor LC column line featuring 1.8, 2.7, and 5 µm SPP core-shell silica.
• Switch to a Raptor FluoroPhenyl LC column when you need more retention and selectivity for basic and hydrophilic compounds than you can achieve on a C18.